منابع مشابه
The children with microcytosis
Microcytosis is decrease of red blood cells (RBCs) size. The RBCs size is measured by the mean corpuscular volume (MCV). In the children, MCV varies by age and sex and so it must be always compared with sex and age-based norms. A MCV less than the 5 percentile defines the children microcytosis . The most frequent causes of microcytosis are iron deficiency anaemia (IDA) and haemoglobinopathies [...
متن کاملEvaluation of microcytosis.
Microcytosis is typically an incidental finding in asymptomatic patients who received a complete blood count for other reasons. The condition is defined as a mean corpuscular volume of less than 80 µm3 (80 fL) in adults. The most common causes of microcytosis are iron deficiency anemia and thalassemia trait. Other diagnoses to consider include anemia of chronic disease, lead toxicity, and sider...
متن کاملHypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis.
Retinitis pigmentosa (RP) is a highly heterogeneous group of disorders characterized by degeneration of the retinal photoreceptor cells and progressive loss of vision. While hundreds of mutations in more than 100 genes have been reported to cause RP, discovering the causative mutations in many patients remains a significant challenge. Exome sequencing in an individual affected with non-syndromi...
متن کاملComparison of erythrocyte indices to differentiate between iron deficiency and alpha-thalassaemias in children with microcytosis and/or hypochromia.
Erythrocyte indices used to differentiate between iron deficiency anaemia (IDA) and thalassaemias have been studied mainly in countries with a high prevalence of IDA or beta-thalassaemias. This study was carried out in the United Arab Emirates where alpha-thalassaemias are prevalent. We studied the predictive value and Youden index of several indices in 85 children aged 6 months to 12 years wit...
متن کاملmTOR inhibition and erythropoiesis: microcytosis or anaemia?
BACKGROUND Anaemia and microcytosis are common post kidney transplantation. The aim of this study was to evaluate the potential role of mammalian target of rapamycin (mTOR) inhibition in the development of anaemia and microcytosis in healthy animals and in human erythroid cultures in vitro. METHODS Rats with normal kidney function were treated with sirolimus (n = 7) or vehicle (n = 8) for 15 ...
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ژورنال
عنوان ژورنال: Italian Journal of Pediatrics
سال: 2014
ISSN: 1824-7288
DOI: 10.1186/1824-7288-40-s1-a14